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Well-written, readable, and superbly illustrated, Cellular and Molecular Immunology, Eleventh Edition, continues
the tradition of excellence established through multiple editions of this bestselling text.
Offering an unparalleled introduction to this complex field, it retains a practical, clinical focus while updating and
revising all content to ensure clarity and comprehension, bringing readers fully up to date with new and emerging
information in this challenging area. It's an ideal resource for medical, graduate, and undergraduate students,
as well as a trusted reference for physicians and scientists.
New to this edition
● Fully revised throughout – including new and expanded coverage of human immune system; neuroimmunology; cancer immunotherapy; intracellular sensors of
innate immunity, therapeutic use of monoclonal antibodies, regulation of migration events during T cell-B cell
interactions, regulatory and transcriptional events in germinal center formation, immunology of infectious diseases
including coronaviruses, human immunodeficiency disorders, and immunology of HIV.
Key Features
● Highlights the implications of immunologic science for the management of human disease, emphasizing clinical relevance throughout.
● Employs a highly accessible writing style that makes difficult concepts easier to understand, and provides clear implications of immunologic science to the management of human disease and clinical practice.
● Provides a highly visual, full-color description of the key immunologic and molecular processes with a fully updated, comprehensive, and consistent art program, including many new and extensively revised illustrations.
● Helps readers grasp the details of experimental observations that form the basis for the science of immunology at the molecular, cellular, and whole-organism levels and draw the appropriate conclusions.
● Includes summary boxes that assist with rapid review and mastery of key material.
● Enhanced eBook version included with purchase. Your enhanced eBook allows access to multiple-choice questions that correspond to each chapter, plus all of the text, figures, and references from the book on a variety of devices.
Author Information
By Abul K. Abbas, MBBS, Emeritus Professor, Department of Pathology, University of California San Francisco,
USA; Andrew H. Lichtman, MD, PhD, Professor of Pathology, Brigham and Women's Hospital, Harvard Medical School,
USA; Shiv Pillai, MD, PhD, Professor of Medicine and Health Sciences and Technology, Harvard Medical School,
Ragon Institute of MGH, MIT and Harvard, USA and Sarah Henrickson, MD, PhD, Assistant Professor, Division of Allergy and Immunology, Department of Pediatrics, Children's Hospital of Philadelphia Department of Pediatrics, Perelman School of Medicine Department of Microbiology, Perelman School of Medicine, USA
Chapter 01 Properties and Overview of Immune Responses
Chapter 02 Cells and Tissues of the Immune System
Chapter 03 Leukocyte Circulation and Migration into Tissues
Chapter 04 Innate Immunity
Chapter 05 Antibodies and Antigens
Chapter 06 Antigen Presentation to T Lymphocytes and the Functions of MHC Molecules
Chapter 07 Immune Receptors and Signal Transduction
Chapter 08 Lymphocyte Development and Antigen Receptor Gene Rearrangement
Chapter 09 Activation of T Lymphocytes
Chapter 10 Differentiation and Functions of CD4+ Effector T Cells
Chapter 11 Differentiation and Functions of CD8+ Effector T Cells
Chapter 12 B Cell Activation and Antibody Production
Chapter 13 Effector Mechanisms of Humoral Immunity
Chapter 14 Specialized Immunity at Epithelial Barriers and in Immune Privileged Tissues
Chapter 15 Immunologic Tolerance and Autoimmunity
Chapter 16 Immunity to Microbes
Chapter 17 Transplantation Immunology
Chapter 18 Immunity to Tumors
Chapter 19 Hypersensitivity Disorders
Chapter 20 Allergy
Chapter 21 Congenital and Acquired Immunodeficiencies
Appendix I Glossary
Appendix II Cytokines
Appendix III Principle Features of Selected CD Molecules
Appendix IV Laboratory Techniques Commonly Used in Immunology